Maurice Michel 11/28/24 Maurice Michel 11/28/24

22. Chemogenomic Screening in a Patient-Derived 3D Fatty Liver Disease Model Reveals the CHRM1-TRPM8 Axis as a Novel Module for Targeted Intervention

Advanced Science, 2025

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Maurice Michel 1/13/24 Maurice Michel 1/13/24

21. Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

iScience, 2024

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Maurice Michel 12/5/23 Maurice Michel 12/5/23

20. Compound Absorption in Polymer Devices Impairs the Translatability of Preclinical Safety Assessments

Advanced Healthcare Materials, 2023

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Maurice Michel 3/16/23 Maurice Michel 3/16/23

19. Target 2035 – an update on private sector contributions

RSC Medicinal Chemistry, 2023

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Maurice Michel 9/21/22 Maurice Michel 9/21/22

18. Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1

ChemMedChem, 2023

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Maurice Michel 8/29/22 Maurice Michel 8/29/22

17. Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies

Clinical and Translational Medicine, 2022

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Maurice Michel 6/24/22 Maurice Michel 6/24/22

16. Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function

Science, 2022

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Maurice Michel 6/19/22 Maurice Michel 6/19/22

15. Nudix hydrolase 18 catalyzes the hydrolysis of active triphosphate metabolites of the antivirals remdesivir, ribavirin, and molnupiravir

Journal of Biological Chemistry, 2022

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Maurice Michel 2/28/22 Maurice Michel 2/28/22

14. Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Nature Cancer, 2022

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Maurice Michel 12/3/21 Maurice Michel 12/3/21

13. Target 2035 – update on the quest for a probe for every protein

RSC Medicinal Chemistry, 2022

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Maurice Michel 5/26/21 Maurice Michel 5/26/21

12. Assembly and Application of a Low Budget Photoreactor

Chemistry Methods, 2021

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Maurice Michel 4/27/21 Maurice Michel 4/27/21

11. NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487

International Journal of Molecular Sciences, 2021

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Maurice Michel 2/10/21 Maurice Michel 2/10/21

10. Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects

Scientific Reports, 2021

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Maurice Michel 11/19/20 Maurice Michel 11/19/20

9. Targeting OGG1 arrests cancer cell proliferation by inducing replication stress

Nucleic Acid Research, 2020

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Maurice Michel 5/29/20 Maurice Michel 5/29/20

8. In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization

Frontiers in Chemistry, 2020

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Maurice Michel 7/5/19 Maurice Michel 7/5/19

7. Computational and Experimental Druggability Assessment of Human DNA Glycosylases

ACS Omega, 2019

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Maurice Michel 11/16/18 Maurice Michel 11/16/18

6. Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Science, 2018

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Maurice Michel 8/25/18 Maurice Michel 8/25/18

5. Targeting BER enzymes in cancer therapy

DNA Repair, 2018

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Maurice Michel 1/3/18 Maurice Michel 1/3/18

4. Synthesis of Galactosylated Glycosylphosphatidylinositol Derivatives from Trypanosoma brucei

Chemistry - A European Journal, 2018

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Maurice Michel 7/26/16 Maurice Michel 7/26/16

3. 19F NMR-Guided Design of Glycomimetic Langerin Ligands

ACS Chemical Biology, 2016

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