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The Michel Lab
Home
Research
People
Publications
Gallery
Contact
Home
Research
People
Publications
Gallery
Contact
Maurice Michel 2/26/26 Maurice Michel 2/26/26

37. A monofunctional-like mutant of DNA glycosylase NTHL1 changes the dynamics of DNA repair during acute oxidative stress

Journal of Biological Chemistry, 2026

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Maurice Michel 12/31/25 Maurice Michel 12/31/25

36. Conformational Control of OGG1 Enables an Efficient AP Lyase Function at AP Sites

ChemRxiv, 2025

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Maurice Michel 12/12/25 Maurice Michel 12/12/25

35. What is in a name? Rethinking SMUG1 in genome maintenance

NAR Cancer, 2025

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Maurice Michel 12/2/25 Maurice Michel 12/2/25

34. Mitochondria-Directed OGG1 Organocatalytic Switches Restore Organelle Function Under Oxidative Stress

ChemRxiv, 2025

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Maurice Michel 11/7/25 Maurice Michel 11/7/25

33. Primary Human Tissue Models for Metabolic Dysfunction-Associated Liver Disease - toward Streamlining Drug Discovery with Patient-Derived Assays

Advanced Biology, 2025

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Maurice Michel 10/28/25 Maurice Michel 10/28/25

32. Nucleobase catalysts for the enzymatic activation of 8-oxoguanine DNA glycosylase 1

RSC Chemical Biology, 2026

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Maurice Michel 10/15/25 Maurice Michel 10/15/25

31. Modulation of OGG1 enzymatic activity by the cellular machinery – have all the boxes been ticked?

DNA Repair, 2025

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Maurice Michel 10/15/25 Maurice Michel 10/15/25

30. Giving an Enzyme Scissors: Serotonin Derivatives as Potent Organocatalytic Switches for DNA Repair Enzyme OGG1

Journal of Medicinal Chemistry, 2025

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Maurice Michel 10/15/25 Maurice Michel 10/15/25

29. OGG1 activation improves T cell resilience to oxidative stress after allo-SCT and T cell engager exposure

Leukemia, 2025

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Maurice Michel 7/23/25 Maurice Michel 7/23/25

28. Protein–ligand data at scale to support machine learning

Nature Reviews Chemistry, 2025

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Maurice Michel 6/24/25 Maurice Michel 6/24/25

27. Detection of antibodies against the African parasite Trypanosoma brucei using synthetic glycosylphosphatidylinositol oligosaccharide fragments

Glycoconjugate Journal, 2025

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Maurice Michel 5/26/25 Maurice Michel 5/26/25

26. Chemical Switching: A Concept Inspired by Strategies from Biocatalysis and Organocatalysis

ChemBioChem, 2025

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Maurice Michel 4/28/25 Maurice Michel 4/28/25

25. Organocatalytic Switches of DNA Glycosylase OGG1 Catalyze a Highly Efficient AP-Lyase Function

Chemistry - A European Journal, 2025

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Maurice Michel 2/18/25 Maurice Michel 2/18/25

24. Virtual fragment screening for DNA repair inhibitors in vast chemical space

Nature Communications, 2025

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Maurice Michel 2/13/25 Maurice Michel 2/13/25

23. Repurposing doxycycline for the inhibition of monkeypox virus DNA polymerase: a comprehensive computational study

in silico Pharmacology, 2025

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Maurice Michel 11/28/24 Maurice Michel 11/28/24

22. Chemogenomic Screening in a Patient-Derived 3D Fatty Liver Disease Model Reveals the CHRM1-TRPM8 Axis as a Novel Module for Targeted Intervention

Advanced Science, 2025

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Maurice Michel 1/13/24 Maurice Michel 1/13/24

21. Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel

iScience, 2024

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Maurice Michel 12/5/23 Maurice Michel 12/5/23

20. Compound Absorption in Polymer Devices Impairs the Translatability of Preclinical Safety Assessments

Advanced Healthcare Materials, 2023

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Maurice Michel 3/16/23 Maurice Michel 3/16/23

19. Target 2035 – an update on private sector contributions

RSC Medicinal Chemistry, 2023

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Maurice Michel 9/21/22 Maurice Michel 9/21/22

18. Optimization of N-Piperidinyl-Benzimidazolone Derivatives as Potent and Selective Inhibitors of 8-Oxo-Guanine DNA Glycosylase 1

ChemMedChem, 2023

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