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The Michel Lab
Home
Research
People
Publications
Gallery
Contact
Home
Research
People
Publications
Gallery
Contact
Maurice Michel 8/29/22 Maurice Michel 8/29/22

17. Synthetic switches of OGG1 control initiation of base excision repair and offer new treatment strategies

Clinical and Translational Medicine, 2022

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Maurice Michel 6/24/22 Maurice Michel 6/24/22

16. Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function

Science, 2022

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Maurice Michel 6/19/22 Maurice Michel 6/19/22

15. Nudix hydrolase 18 catalyzes the hydrolysis of active triphosphate metabolites of the antivirals remdesivir, ribavirin, and molnupiravir

Journal of Biological Chemistry, 2022

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Maurice Michel 2/28/22 Maurice Michel 2/28/22

14. Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress

Nature Cancer

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Maurice Michel 12/3/21 Maurice Michel 12/3/21

13. Target 2035 – update on the quest for a probe for every protein

RSC Medicinal Chemistry

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Maurice Michel 5/26/21 Maurice Michel 5/26/21

12. Assembly and Application of a Low Budget Photoreactor

Chemistry Methods

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Maurice Michel 4/27/21 Maurice Michel 4/27/21

11. NEIL1 and NEIL2 Are Recruited as Potential Backup for OGG1 upon OGG1 Depletion or Inhibition by TH5487

International Journal of Molecular Sciences

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Maurice Michel 2/10/21 Maurice Michel 2/10/21

10. Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects

Scientific Reports

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Maurice Michel 11/19/20 Maurice Michel 11/19/20

9. Targeting OGG1 arrests cancer cell proliferation by inducing replication stress

Nucleic Acid Research

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Maurice Michel 5/29/20 Maurice Michel 5/29/20

8. In silico Druggability Assessment of the NUDIX Hydrolase Protein Family as a Workflow for Target Prioritization

Frontiers in Chemistry

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Maurice Michel 7/5/19 Maurice Michel 7/5/19

7. Computational and Experimental Druggability Assessment of Human DNA Glycosylases

ACS Omega

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Maurice Michel 11/16/18 Maurice Michel 11/16/18

6. Small-molecule inhibitor of OGG1 suppresses proinflammatory gene expression and inflammation

Science

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Maurice Michel 8/25/18 Maurice Michel 8/25/18

5. Targeting BER enzymes in cancer therapy

DNA Repair

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Maurice Michel 1/3/18 Maurice Michel 1/3/18

4. Synthesis of Galactosylated Glycosylphosphatidylinositol Derivatives from Trypanosoma brucei

Chemistry - A European Journal

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Maurice Michel 7/26/16 Maurice Michel 7/26/16

3. 19F NMR-Guided Design of Glycomimetic Langerin Ligands

ACS Chemical Biology

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Maurice Michel 11/1/12 Maurice Michel 11/1/12

2. Glycosylphosphatidylinositols of Protozoan Parasites

Trends in Glycoscience and Glycotechnology

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Maurice Michel 11/1/12 Maurice Michel 11/1/12

1. A general and convergent synthesis of diverse glycosylphosphatidylinositol glycolipids

Chemical Science

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